Manchester, New Hampshire, historically known for its industrial roots, is experiencing a remarkable transformation into a burgeoning tech hub. This evolution is driven by a combination of innovative startups, supportive organizations, and strategic initiatives aimed at fostering technological advancement.
Emergence of Biofabrication
One of the most significant developments in Manchester’s tech landscape is its leadership in biofabrication—the manufacturing of biological products such as tissues and organs. The Advanced Regenerative Manufacturing Institute (ARMI), established in 2016, has been at the forefront of this movement. In December 2025, ARMI broke ground on a new biomanufacturing facility and workforce training center in the Millyard district, signaling a commitment to scaling biofabrication from research to production. This facility is expected to be completed by 2027 and is anticipated to generate over 9,000 direct jobs and an additional 35,000 indirect employment opportunities in the region.
Supportive Ecosystem for Startups
The city’s tech growth is bolstered by organizations like the New Hampshire Tech Alliance (NHTA), which supports companies at every stage of development. NHTA’s mission is to create connections, encourage growth, and advocate for the tech sector, contributing to a vibrant ecosystem that nurtures innovation.
Educational Initiatives and Workforce Development
Educational institutions are playing a pivotal role in preparing a skilled workforce to meet the demands of the growing tech industry. The Community College System of New Hampshire (CCSNH) has introduced apprenticeship programs in biofabrication, aiming to equip students with the necessary skills for careers in this emerging field.
Additionally, the University of New Hampshire at Manchester has launched the STEM-MoBILE, a traveling lab that introduces biofabrication to schools and communities across the state. This initiative seeks to educate individuals of all ages about biofabrication and the exciting career opportunities it offers.
Community Spaces for Innovation
Manchester Makerspace, founded in 2015, provides a collaborative environment where makers, artists, and entrepreneurs can access shared tools and resources. This community-driven space supports innovation and creativity, lowering barriers for those eager to learn and create.
Manchester’s transformation into a tech hub is a testament to the city’s adaptability and commitment to innovation. Through strategic partnerships, educational initiatives, and community support, Manchester is positioning itself as a leader in technology and biofabrication, promising a bright future for its residents and the broader region.

